Lung T1 is sensitive to lung pathology, tissue and perfusion, and can be used to the calculation of quantitative DCE perfusion metrics. However, no comparisons have been made of common MRI T1 mapping sequences in the human lung. The aim of this work was to compare Look-Locker and variable flip angle T1 mapping sequences in phantoms and in vivo, in the lung, liver and blood. T1 measured in the phantom, blood and liver was significantly lower when measured using a Look-Locker acquisition than VFA, whereas lung T1 was significantly higher when measured using Look-Locker acquisition than when measured using VFA.
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