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Abstract #3300

Resolving the fat-water ambiguity based on T1 difference

Hao Peng1,2, Liwen Wan1, Qian Wan1, Jianxun Lv1, Chuanli Cheng1, Yi Wang3, Wenzhong Liu2, Xin Liu1, Hairong Zheng1, and Chao Zou1
1Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institute of Advanced Technology,Chinese Academy of Sciences, Shenzhen, China, 2Key Laboratory of Imaging Processing and Intelligence Control, School of Artificial Intelligence and Automation, Huazhong University of Science & Technology, Wuhan, China, 3Department of Radiology, Peking University Peoples Hospital, Beijing, China

Fat-water ambiguity is an intrinsic problem from chemical shift encoded imaging model. When this problem is not well solved throughout the whole image, fat-water swaps appear and result in inaccurate fat quantification. The success of solving the ambiguity relies on pre-assumptions, e.g. the magnetic field continuity or the prior knowledge of the adipose/aqueous tissue distribution etc. In our work, we proposed to incorporate the T1 difference of fat and water to help solve the ambiguity problem. Proposed method can obtain PDFF and accurate T1 mapping simultaneously with B1+ correction. The sequence could cover the whole liver within a single breath-hold.

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