Abstract #3312

MR T1Ρ preparations: B1 and B0 inhomogeneity response on 3T and 7T systems

Jeehun Kim^1,2, Qi Peng³, Can Wu^4,5, and Xiaojuan Li^1,6

¹Department of Biomedical Engineering, Program of Advanced Musculoskeletal Imaging (PAMI), Cleveland Clinic, Cleveland, OH, United States, ²Case Western Reserve University, Cleveland, OH, United States, ³Department of Radiology, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY, United States, ⁴Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States, ⁵Philips Healthcare, Andover, MA, United States, ⁶Department of Diagnostic Radiology, Cleveland Clinic, Cleveland, OH, United States

Quantitative T_1ρ mapping is a promising biomarker for detecting tissue compositional changes at early stages of diseases. For reliable and reproducible measurements, T_1ρ preparation pulses should be robust to B₀ and B₁ inhomogeneity. In this work, six different preparation schemes were evaluated in terms of their responses to B₀ and B₁ inhomogeneities on agarose phantoms and volunteers using both 3T and 7T MRI systems.

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