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Abstract #3312

MR T1Ρ preparations: B1 and B0 inhomogeneity response on 3T and 7T systems

Jeehun Kim1,2, Qi Peng3, Can Wu4,5, and Xiaojuan Li1,6
1Department of Biomedical Engineering, Program of Advanced Musculoskeletal Imaging (PAMI), Cleveland Clinic, Cleveland, OH, United States, 2Case Western Reserve University, Cleveland, OH, United States, 3Department of Radiology, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY, United States, 4Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States, 5Philips Healthcare, Andover, MA, United States, 6Department of Diagnostic Radiology, Cleveland Clinic, Cleveland, OH, United States

Quantitative T mapping is a promising biomarker for detecting tissue compositional changes at early stages of diseases. For reliable and reproducible measurements, T preparation pulses should be robust to B0 and B1 inhomogeneity. In this work, six different preparation schemes were evaluated in terms of their responses to B0 and B1 inhomogeneities on agarose phantoms and volunteers using both 3T and 7T MRI systems.

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