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Abstract #3313

Efficient Phase Cycling Strategy for High Resolution Three-Dimensional GRE Quantitative Mapping

Qi Peng1, Can Wu2,3, Jee Hun Kim4,5, and Xiaojuan Li4,5,6
1Department of Radiology, Albert Einstein College of Medicine, Bronx, NY, United States, 2Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States, 3Philips Healthcare, Andover, MA, United States, 4Program of Advanced Musculoskeletal Imaging (PAMI), Cleveland Clinic, Cleveland, OH, United States, 5Department of Biomedical Engineering, Cleveland Clinic, Cleveland, OH, United States, 6Department of Diagnostic Radiology, Cleveland Clinic, Cleveland, OH, United States

Magnetization-prepared gradient echo (MP-GRE) sequences have been commonly used for quantitative MRI in the literature to improve imaging speed. Paired acquisitions with RF phase-cycling could eliminate image blurring due to longitudinal relaxation and loss of MP contrast along the GRE readouts, with doubled scan time. This study introduces a novel unpaired phase cycling strategy to eliminate the time penalty with reduced sensitivity to B0 field inhomogeneities for high resolution quantitative mapping in MP-GRE sequences. The feasibility and efficacy of this strategy were demonstrated in both phantom and human studies.

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