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Abstract #3340

A universal framework to build digital reference objects for evaluation of quantitative MRI analysis with multiple measurements

Henry Szu-Meng Chen1, Brian A Taylor1, Joshua P Yung1, Ping Hou1, R. Jason Stafford1, and Ho-Ling A Liu1
1Imaging Physics, MD Anderson Cancer Center, Houston, TX, United States

We propose a framework to easily design and generate digital reference object (DRO) s that conforms with DICOM standard for testing quantitative MRI analysis. The method focuses on using existing phantom scan as the basis and allows user to customize the phantom’s geometry and signal model. We generated a number of DRO for T2* and DSC quantitation and analyzed them with two different software as proof-of-concept.

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