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Abstract #3353

3D printed head-shaped phantom with lipid layer and brain-mimicking metabolites for 7 Tesla MRI and MRSI 

Rita Schmidt1,2, Ghil Jona3, and Edna Furman-Haran2,3
1Neurobiology, Weizmann Institute of Science, Rehovot, Israel, 2The Azrieli National Institute for Human Brain Imaging and Research, Weizmann Institute of Science, Rehovot, Israel, 3Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel

Moving to ultra-high fields (≥7T), the inhomogeneity of both RF and static magnetic fields increases, which motivates to design a realistic head-shaped phantom. In this study, a 3D-printed head-shaped phantom with brain mimicking metabolites and lipid layer examined for 7T MRI and MRSI. The phantom was designed to resemble the brain with respect to B0 and B1 distributions, metabolites and lipid layer. We examined it for 1H MRS and MRSI, especially in the lipid layer vicinity. We also demonstrated in EPI that the Fat Suppression pulse flip angle can be optimized to minimize the lipid artifact and reduce the SAR.

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