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Abstract #3364

A phantom-based method for MRI relaxation time mapping data validation and harmonization

Davide Cicolari1, Domenico Lizio2, Patrizia Pedrotti3, Monica Teresa Moioli2, Alessandro Lascialfari1, Manuel Mariani1, and Alberto Torresin2,4
1Department of Physics, University of Pavia, Pavia, Italy, 2Department of Medical Physics, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy, 3Department of Cardiology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy, 4Department of Physics, University of Milan, Milan, Italy

A method for the MRI relaxation time measurement validation and harmonization is proposed: it relies on a phantom composed of vials filled with different concentrations of MnCl2 aqueous solutions, whose relaxation times are characterized as a function of both concentration and temperature, employing NMR techniques. The accuracy and the precision of fast mapping sequences developed for cardiac applications are better quantified through, respectively, the phantom characterization and the SD maps analysis. Scan-dependent recalibrations of the relaxation time maps can be performed relying on the ground-truth NMR values of the phantom, aiming to clinical intra- and inter-center harmonization.

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