Meeting Banner
Abstract #3369

Layer-specific activation of prediction in the human midcingulate cortex

Jiajia Yang1,2, Masaki Fukunaga3, Yinghua Yu2,4, Laurentius Huber5, Peter A Bandettini2, and Norihiro Sadato3
1Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, Okayama, Japan, 2Section on Functional Imaging Methods, National Institute of Mental Health, Bethesda, MD, United States, 3Division of Cerebral Integration, National Institute for Physiological Sciences, Okazaki, Japan, 4Center for Information and Neural Networks, National Institute of Information and Communications Technology, Suita, Japan, 5Department of Cognitive Neuroscience, Maastricht University, Maastricht, Netherlands

The human brain is constantly generating and updating predictions. The midcingulate cortex (MCC) is one of the areas that contribute to prediction processing, while MCC layer-specific function remains unknown. In the present study, we used a tactile index finger prediction task that consists of sequential finger poking during high-resolution (0.76mm) BOLD and VASO fMRI at 7T to investigate how the prediction activity changes across layers in the human MCC. We found the double-peak activity feature across MCC layers for all prediction tasks, and the enhanced activity within MCC superficial layers may reflect the prediction error processing.

This abstract and the presentation materials are available to members only; a login is required.

Join Here