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Abstract #3376

Mapping of Whole-brain Resting-State Networks with Half-millimetre Resolution using TR-external EPIK at 7T

Seong Dae Dae Yun1, Patricia Pais-Roldán1, Nicola Palomero-Gallagher2,3,4, and N. Jon Shah1,5,6,7
1Institute of Neuroscience and Medicine 4, INM-4, Forschungszentrum Juelich, Juelich, Germany, 2Institute of Neuroscience and Medicine 1, INM-1, Forschungszentrum Juelich, Juelich, Germany, 3C. & O. Vogt Institute for Brain Research, Heinrich-Heine-University, Duesseldorf, Germany, 4Department of Psychiatry, Psychotherapy and Psychosomatics, Medical Faculty, RWTH Aachen, Aachen, Germany, 5Institute of Neuroscience and Medicine 11, INM-11, JARA, Forschungszentrum Juelich, Juelich, Germany, 6JARA - BRAIN - Translational Medicine, Aachen, Germany, 7Department of Neurology, RWTH Aachen University, Aachen, Germany

Mapping of resting-state networks has been performed in numerous studies to investigate overall brain function and its underlying connectivity. However, attempts to acquire resting-state fMRI data with high spatial resolution have been hampered by the current technical limitations. The spatial resolution from recent submillimetre-resolution fMRI studies still remains around 0.7 × 0.7 × 0.7 mm3, with only partial brain coverage. This work employs a novel high-resolution fMRI method, TR-external EPIK, to perform resting-state fMRI with half-millimetre in-plane resolution and whole-brain coverage at 7T. Various resting-state networks over the whole-brain have been identified with high mapping fidelity onto the cortical ribbon.

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