Tracing and monitoring the growth of transplanted stem cells in vivo has become a focus of research. The purpose of this study is to realize the dynamic tracing of transplanted mesenchymal stem cells labeled with nano-iron(SPIO-huc-MSCs), and preliminarily explore the feasibility of indirect tracing of SPIO-huc-MSCs by QSM technology. The results show that susceptibility values in the areas containing iron are significantly different from those in the normal spinal cord, which indicates that the iron concentration in the injured area decreases gradually. By quantifying iron concentration, QSM technology can be used to dynamically trace SPIO labeled stem cells in vivo.
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