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Abstract #3467

Quantitative Multimodal Magnetic Resonance Imaging for the Evaluation of Dysthyroid Optic Neuropathy

Mengsha Zou1, Hongzhang Zhu1, Yunzhu Wu2, and Zhiyun Yang1
1Radiology, The first affiliated hospital of Sun Yet-sen University, Guangzhou, China, 2MR Sicentific Marketing, Siemens Healthineers, Shanghai, China

Dysthyroid optic neuropathy (DON) is one of the most severe types of Graves orbitopathy (GO) and requires urgent treatment to prevent blindness. However, DON is frequently difficult to diagnose clinically in its early stages because of confounding signs and symptoms of congestive orbitopathy. In our study, we evaluate orbital condition of DON patients by using quantitative multimodal MRI, which include anatomical and functional indicators. We found that mMI (at 21 mm) combined with the mean T2 value of the optical nerve can use as an effective imaging indicator for detecting DON.

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