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Abstract #3466

Assessment of Spinal Cord Diffusivity in Degenerative Cervical Myelopathy after Spinal Fusion Decompression

Kevin M Koch1, V. Emre Arpinar1, and Matthew Budde2
1Radiology, Medical College of Wisconsin, Milwaukee, WI, United States, 2Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, United States

Metal artifacts from commonly-encountered spinal fusion stabilization hardware have historically confounded quantitative MRI (qMRI) research investigations of the injured and damaged spinal cord in human subjects. This report provides preliminary analysis of metal-artifact suppressed multi-spectral diffusion qMRI collected on instrumented degenerative cervical spondylotic myelopathy (CSM) subjects. The results of the study demonstrate group trends of reduced diffusivity in the CSM group at spinal cord levels fused by hardware. This is a unique finding in instrumented CSM subjects that may offer unique insight into the impact of spinal fusion interventions on conventional qMRI measures of the spinal cord.

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