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Abstract #3562

Imaging Gas-Exchange Lung Function using Density-Weighted MRSI and Hyperpolarised 129Xe Gas

Rolf F Schulte1, Guilhem J Collier2, James Ball2, Graham Norquay2, Madhwesha Rao2, and Jim M Wild2
1GE Healthcare, Munich, Germany, 2POLARIS, Department of Infection Immunity & Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom

3D density-weighted MRSI in combination with a frequency-tailored RF excitation pulse was designed, implemented and used to detect xenon gas in the lungs and xenon dissolved in lung tissue and blood. These images were used to calculate quantitative ratio maps of tissue-to-gas, blood-to-gas, and blood-to-tissue with good SNR.

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