Abstract #3563

A 129Xe/1H Switched Frequency High Pass Birdcage Coil for Hyperpolarized 129Xe Gas Lung Imaging in Neonates at 1.5 T

Ronald Pratt¹, Randy Giaquinto¹, Wolfgang Loew¹, Christopher Ireland¹, Neil Stewart^2,3, Nara Higano², Jason Woods², and Charles Dumoulin¹

¹Imaging Research Center/Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States, ²Center for Pulmonary Imaging Research/Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States, ³POLARIS, Imaging Sciences, Dept of Infection, Immunity & Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom

Production of hyperpolarized ¹²⁹Xe gas has opened new frontiers for imaging lung anatomy and function using MRI. Our institution has the goal of using hyperpolarized ¹²⁹Xe gas for MR imaging of neonatal lungs at 1.5 T. To realize this goal, it is essential that the RF coil used for imaging operate at both the ¹²⁹Xe and ¹H frequencies. This report provides fabrication details of a novel ¹²⁹Xe/¹H switched frequency transmit/receive 16 rung high-pass birdcage RF coil. Images collected with hyperpolarized ¹²⁹Xe gas and water in phantoms demonstrate that the coil provides excellent image quality at both frequencies.

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