Abstract #3577

Dual-Phase Imaging of Cardiac Metabolism using Hyperpolarized [1-13C]Pyruvate

Junjie Ma¹, Craig R. Malloy^1,2,3, Crystal E. Harrison¹, James Ratnakar¹, Galen D. Reed⁴, Vlad G. Zaha^1,2, and Jae Mo Park^1,3,5

¹Advanced Imaging Research Center, UT SOUTHWESTERN MEDICAL CENTER, Dallas, TX, United States, ²Internal Medicine, UT Southwestern Medical Center, Dallas, TX, United States, ³Radiology, UT Southwestern Medical Center, Dallas, TX, United States, ⁴GE Healthcare, Dallas, TX, United States, ⁵Electrical and Computer Engineering, UT Dallas, Richardson, TX, United States

A dual-phase ¹³C imaging sequence that acquires multi-echo images of hyperpolarized [1-¹³C]pyruvate, [1-¹³C]lactate, [1-¹³C]alanine and [¹³C]bicarbonate was implemented to acquire metabolic data at both end systole and end diastole from the human heart in a single injection. The proposed method was demonstrated in short-axis and long-axis ventricle views.

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