In this work we compare non-contrast enhanced imaging methods such as native T1, T2 mapping and cardiac diffusion tensor imaging, to ECV measurements in a longitudinal porcine study of myocardial infarction. T2 is elevated only during the acute stage. During the transition from acute to chronic stage T1 remains unchanged and ECV as well as MD progressively increase while FA decreases. During the acute stage, T2 mapping provides highest contrast whereas diffusional metrics showed larger changes during the chronic stage compared to native relaxometry showing the potential of DTI for probing dynamic myocardial changes upon an ischemic event.
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