Simultaneous acquisition of diffusion tensor imaging (DTI) and magnetic resonance elastography (MRE) has been proven feasible in a preliminary study of in vivo human brain. However, the experimental parameters have to be optimized in order to prevent mutual interferences of DTI and MRE acquisitions. We identified in simulations three experimental parameter sets for in vivo human brain DTI-MRE that we classify as good, moderate and poor with regard to optimization and present a pilot study using these parameter sets. The experimental results verify the simulations as we found the best performance of DTI-MRE for the good parameters set.
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