The study aims to assess quantitative imaging (QI) metrics from pre-treatment (TX) non-gaussian intravoxel incoherent DW- and fast exchange regime (FXR) DCE-MRI for predicting locoregional failure (LRF) in nasopharyngeal carcinoma (NPC) patients. Cumulative incidence analysis (CIA) was performed on the two subgroups dichotomized with Youden’s index. Competing-risks regression based on Fine and Gray’s (FG) proportional sub hazards model was used to estimate survival subdistribution hazard ratios (SHRs). The pre-TX ADC, D, f, and ti cutoff values from CIA analysis and K cutoff value from the competing risk regression analysis indicated these QI’s could predict the LRF in NPC patients.
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