Abstract #3750

Adding an absolute chest position regressor to RETROICOR for spinal cord fMRI during atypical breathing patterns

Neha A Reddy^1,2, Andrew D Vigotsky^1,3, Rachael C Stickland², and Molly G Bright^1,2

¹Department of Biomedical Engineering, Northwestern University, Evanston, IL, United States, ²Department of Physical Therapy and Human Movement Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States, ³Department of Statistics, Northwestern University, Evanston, IL, United States

RETROICOR (Retrospective Image Correction) is a commonly used technique for physiological noise correction, but it may not be optimal in its standard implementation for use in studies of the human spinal cord involving atypical breathing patterns. We test the inclusion of an absolute chest position regressor derived from respiratory belt data, in addition to standard RETROICOR regressors, in modeling fMRI scans of the cervical spinal cord with and without breath-hold challenges. The chest position regressor may be a simple approach towards explaining additional noise variance in spinal cord fMRI data during breath-hold tasks.

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