In quantitative 129Xe gas exchange MRI, the RBC/barrier ratio is emerging as a robust and important functional metric. However, it depends strongly on how it is measured, specifically on flip angle and repetition time. Moreover, we don’t yet have a clear understanding of its expected range in healthy subjects. Here, we demonstrate that by combining a physical diffusion model of 129Xe signal recovery with the recently introduced concept of flip angle to TR-equivalence, we can estimate the “structural limit” for the maximum RBC/barrier ratio expected in healthy adult subjects at any TR and flip angle.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords