Meeting Banner
Abstract #3794

A Comparison of Multi-breath Wash-in/Wash-out and RF-Contrast Hyperpolarized 129Xe Imaging Schemes for Quantifying Fractional Ventilation

Luis Loza1, Tahmina Achekzai1, Stephen Kadlecek1, Hooman Hamedani1, Ian Duncan1, and Rahim R. Rizi2
1University of Pennsylvania, Philadelphia, PA, United States, 2Radiology, University of Pennsylvania, Philadelphia, PA, United States

Fractional ventilation, a metric denoting per-breath pulmonary gas replacement, has been shown to be sensitive to disease-induced alterations in ventilation in diseases such as emphysema. We have developed two discrete techniques for measuring FV using hyperpolarized 129Xe MR imaging and demonstrated their acquisition in a rat. Although the two techniques yield different FV maps, these two techniques offer both a quick and cost-effective method and a longer, robust method for probing pulmonary ventilation.

This abstract and the presentation materials are available to members only; a login is required.

Join Here