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Abstract #3855

Water/fat separation using multiple decoder U-Net architecture (MDWF-Net) for accurate R2* measurements

Juan Pablo Meneses1,2, Cristobal Arrieta1,2, Gabriel della Maggiora1,2, Pablo Irarrazaval1,2,3,4, Cristian Tejos1,2,4, Marcelo Andia1,2,5, Carlos Sing Long1,2,3,6,7, and Sergio Uribe1,2,5
1Biomedical Imaging Center, Pontificia Universidad Catolica de Chile, Santiago, Chile, 2ANID – Millennium Science Initiative Program – Millennium Nucleus for Cardiovascular Magnetic Resonance, Santiago, Chile, 3Institute for Biological and Medical Engineering, Pontificia Universidad Catolica de Chile, Santiago, Chile, 4Department of Electrical Engineering, Pontificia Universidad Catolica de Chile, Santiago, Chile, 5Radiology Department, School of Medicine, Pontificia Universidad Catolica de Chile, Santiago, Chile, 6Institute for Mathematical & Computational Engineering, Pontificia Universidad Catolica de Chile, Santiago, Chile, 7ANID – Millennium Science Initiative Program – Millennium Nucleus for Discovery of Structure in Complex Data, Santiago, Chile

Proton density fat fraction (PDFF) and $$$R_2^*$$$, key biomarkers associated to liver disease, can be obtained by solving the water/fat separation problem. Convolutional Neural Networks (CNN) have been proposed for solving this problem. However, proposed solutions have not achieved accurate $$$R_2^*$$$ mapping. We introduce MDWF-Net, a CNN model for computing high quality water-fat, $$$R_2^*$$$ and field mapping from abdominal acquisitions. The results were evaluated considering error and structural similarity and compared against a U-Net. We also evaluated ROIs in the liver for PDFF and $$$R_2^*$$$. The proposed MDWF-Net overperforms the original U-Net, especially for $$$R_2^*$$$ maps, even with fewer echoes.

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