Knee osteoarthritis (KOA) is characterized by pain and limitation in the range of knee joint motion with resultant disability in a substantial proportion of elderly subjects, and infrapatellar fat pad (IPFP) alterations play an important role in the progress of KOA(1,2). IPFP damage causes a direct change in the proportion of fat in the tissue to water and could be evaluated by magnetic resonance imaging (MRI)(3,4). Fat fraction (FF) and the T2* relaxation time can detect the water and fat changes in IPFP. In this study, IPFP was quantitatively estimated by FF and T2* using modified DIXON (mDIXON) technique.
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