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Abstract #3869

Fat fraction and T2* evaluation of the Infrapatellar Fat Pad in Varying Degrees of Knee Osteoarthritis

Yanjun Chen1, Xintao Zhang1, Mianwen Li1, Lijie Zhong1, Jian Wang1, Yingjie Mei2, and Xiaodong Zhang1
1The Third Affiliated Hospital, Southern Medical University, Guangzhou, China, 2China International Center, Philips Healthcare, Guangzhou, China

Knee osteoarthritis (KOA) is characterized by pain and limitation in the range of knee joint motion with resultant disability in a substantial proportion of elderly subjects, and infrapatellar fat pad (IPFP) alterations play an important role in the progress of KOA(1,2). IPFP damage causes a direct change in the proportion of fat in the tissue to water and could be evaluated by magnetic resonance imaging (MRI)(3,4). Fat fraction (FF) and the T2* relaxation time can detect the water and fat changes in IPFP. In this study, IPFP was quantitatively estimated by FF and T2* using modified DIXON (mDIXON) technique.

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