Abstract #3901

The Usefulness of Variable-density Stack-of-Stars Acquisition in Dynamic Gadolinium-Enhanced MRI of Prostate Cancer: A Preliminary Study

Shintaro Horii¹, Yoshiko Ueno², Yuichiro Somia¹, Ryuji Shimada¹, Keitaro Sofue², Yasuyo Urase², Wakiko Tani¹, Yu Ueda³, Akiko Kusaka¹, and Takamichi Murakami²

¹Center for Radiology and Radiation Oncology, Kobe University Hospital, kobe, Japan, ²Department of Radiology, Kobe University Graduate School of Medicine, Kobe University Hospital, kobe, Japan, ³Philips Japan MR Clinical Science, tokyo, Japan

This study aimed to compare the image quality and the quantitative DCE-MRI parameters using the k-space weighted image contrast reconstruction with variable-density golden angle stack-of-stars acquisition (4D-FB) to those of the conventional 3D-T1W turbo field echo sequence (e-THRIVE) in prostate cancer (PCa). Image quality assessment and the receiver operating characteristic curve (AUC) analysis of quantitative DCE-MRI parameters in discrimination PCa from normal tissue were performed. 4D-FB showed significantly higher SNR compared to e-THRIVE. No significant differences were observed in AUCs for each quantitative DCE-MRI parameter. 4D-FB may improve image quality of DCE-MRI with keeping effective pharmacokinetic information in PCa assessment.

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