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Abstract #3901

The Usefulness of Variable-density Stack-of-Stars Acquisition in Dynamic Gadolinium-Enhanced MRI of Prostate Cancer: A Preliminary Study

Shintaro Horii1, Yoshiko Ueno2, Yuichiro Somia1, Ryuji Shimada1, Keitaro Sofue2, Yasuyo Urase2, Wakiko Tani1, Yu Ueda3, Akiko Kusaka1, and Takamichi Murakami2
1Center for Radiology and Radiation Oncology, Kobe University Hospital, kobe, Japan, 2Department of Radiology, Kobe University Graduate School of Medicine, Kobe University Hospital, kobe, Japan, 3Philips Japan MR Clinical Science, tokyo, Japan

This study aimed to compare the image quality and the quantitative DCE-MRI parameters using the k-space weighted image contrast reconstruction with variable-density golden angle stack-of-stars acquisition (4D-FB) to those of the conventional 3D-T1W turbo field echo sequence (e-THRIVE) in prostate cancer (PCa). Image quality assessment and the receiver operating characteristic curve (AUC) analysis of quantitative DCE-MRI parameters in discrimination PCa from normal tissue were performed. 4D-FB showed significantly higher SNR compared to e-THRIVE. No significant differences were observed in AUCs for each quantitative DCE-MRI parameter. 4D-FB may improve image quality of DCE-MRI with keeping effective pharmacokinetic information in PCa assessment.

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