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Abstract #3904

A comparison study of the value of Diffusion Kurtosis Imaging and Amide Proton Transfer imaging in the evaluation of prostate cancer

Huijia Yin1, Dongdong Wang1, Ruifang Yan1, Xuekun Li1, Kaiyu Wang2, and Dongming Han1
1MR, the First Affiliated Hospital of Xinxiang Medical University, Xinxiang, China, 2MR Research China,GE Healthcare, Xinxiang, China

This study explored the diagnostic value of APT and DKI in prostate cancer(PCa) and benign prostatic hyperplasia(BPH), and compared the diagnostic advantages of the two techniques and their relationship with the risk of prostate cancer. Our study have shown that APT and DKI both can differentiate PCa and BPH, but DKI has higher diagnostic value, and have strong correlation with Gleason score.They all have the potential to be used in routine clinical practice as new indicators to evaluate the risk of PCa, and to help early diagnosis and personalized diagnosis and treatment of PCa.

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