Prostate cancer is the most common tumor in men. 23Na-MRI provides complementary information to multiparametric-MRI. Tissue sodium concentration (TSC) quantification depends on sodium references-usually external phantoms.
This study investigates TSC-quantification based on internal references (iliac-artery).
23Na-MRI of 19 male patients with suspected PCa was included. TSC in the prostate was quantified based on external reference vials and based on the iliac artery.
Three patients showed a PI-RADs-5 lesion and had an elevated TSC which is in alignment with prvious studies. No significant differences between both methods were found in the whole prostate.
Internal references for TSC quantification could simplify 23Na-MRI.