Abstract #3903

23Na MRI in Patients with suspected Prostate Cancer: External and Internal References for Quantification of Tissue Sodium Concentration

Anne Adlung¹, Fabian Tollens², Nadia Karina Paschke¹, Jennifer Hümsch¹, Niklas Westhoff³, Daniel Hausmann^2,4, Lothar Rudi Schad¹, Dominik Nörenberg², and Frank Gerrit Zöllner^1,5

¹Computer Assisted Clinical Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany, ²Department of Radiology and Nuclear Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany, ³Department of Urology and Urosurgery, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany, ⁴Department of Radiology, Kantonspital Baden, Baden, Switzerland, ⁵Mannheim Institute for Intelligent System in Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany

Prostate cancer is the most common tumor in men. ²³Na-MRI provides complementary information to multiparametric-MRI. Tissue sodium concentration (TSC) quantification depends on sodium references-usually external phantoms.

This study investigates TSC-quantification based on internal references (iliac-artery).

²³Na-MRI of 19 male patients with suspected PCa was included. TSC in the prostate was quantified based on external reference vials and based on the iliac artery.

Three patients showed a PI-RADs-5 lesion and had an elevated TSC which is in alignment with prvious studies. No significant differences between both methods were found in the whole prostate.

Internal references for TSC quantification could simplify ²³Na-MRI.

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