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Abstract #3906

Head-to-head comparison of PSMA-PET/CT and ferumoxtran-10-enhanced MRI for the diagnosis of lymph node metastases in prostate cancer patients

Melline Gabrielle Maria Schilham1, Patrik Zamecnik1, Bas Israel1, Bastiaan Privé1, Mark Rijpkema1, Jelle Barentsz1, James Nagarajah1, Martin Gotthardt1, and Tom Scheenen1
1Medical Imaging, Radboudumc, Nijmegen, Netherlands

In this head-to-head comparison study, 45 prostate cancer patients underwent both USPIO-enhanced MRI (nano-MRI) and prostate-specific membrane antigen PET/CT for the purpose of lymph node staging. The results of both scans were compared on number, size and location of suspicious lymph nodes. Both modalities identified suspicious LNs which were missed by the other. Both modalities identified suspicious LNs in all anatomical regions of the pelvis, however nano-MRI appeared to be superior in detecting smaller suspicious LNs.

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