Abstract #3914

Contrast-enhanced T1-weighted DANTE-SPACE, PETRA, and MPRAGE: clinical evaluation comparison in intracranial tumor patients at 3T

Qing Fu^1,2, Qi-guang Cheng^1,2, Xiao-yong Zhang³, Xiang-chuang Kong^1,2, Ding-xi Liu^1,2, Yi-hao Guo⁴, John Grinstead⁵, Zi-qiao Lei^1,2, and Chuan-sheng Zheng^1,2

¹Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, ²Hubei Province Key Laboratory of Molecular Imaging, Wuhan, China, ³Centers for Biomedical Engineering, University of Science and Technology of China, Hefei, China, ⁴MR Collaboration, Siemens Healthcare Ltd., Guangzhou, China, ⁵Siemens Medical Solutions USA, Inc., Portland, OR, United States

Three dimensional (3D) T1-weighted sequences are commonly used for imaging of contrast-enhanced brain tumors, but enhancement of small vessels may mimic imaging of focal lesions, thereby hindering accurate diagnosis. This study validated that when compared with PETRA and conventional MPRAGE, DANTE-SPACE detects more small metastases with better CNR between lesions and surrounding parenchyma, and may be useful for differential tumor diagnosis because of its blood signal suppression abilities; PETRA could achieve similar detection for brain tumors and quieter acoustic noise level when compared with MPRAGE.

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