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Abstract #3914

Contrast-enhanced T1-weighted DANTE-SPACE, PETRA, and MPRAGE: clinical evaluation comparison in intracranial tumor patients at 3T

Qing Fu1,2, Qi-guang Cheng1,2, Xiao-yong Zhang3, Xiang-chuang Kong1,2, Ding-xi Liu1,2, Yi-hao Guo4, John Grinstead5, Zi-qiao Lei1,2, and Chuan-sheng Zheng1,2
1Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, 2Hubei Province Key Laboratory of Molecular Imaging, Wuhan, China, 3Centers for Biomedical Engineering, University of Science and Technology of China, Hefei, China, 4MR Collaboration, Siemens Healthcare Ltd., Guangzhou, China, 5Siemens Medical Solutions USA, Inc., Portland, OR, United States

Three dimensional (3D) T1-weighted sequences are commonly used for imaging of contrast-enhanced brain tumors, but enhancement of small vessels may mimic imaging of focal lesions, thereby hindering accurate diagnosis. This study validated that when compared with PETRA and conventional MPRAGE, DANTE-SPACE detects more small metastases with better CNR between lesions and surrounding parenchyma, and may be useful for differential tumor diagnosis because of its blood signal suppression abilities; PETRA could achieve similar detection for brain tumors and quieter acoustic noise level when compared with MPRAGE.

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