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Abstract #3915

Evaluation of Ultrafast Post-Contrast Wave-CAIPI 3D-T1 MPRAGE Compared to Standard 3D-T1 MPRAGE for Evaluating Enhancing Lesions on 3T MRI.

Augusto Lio M. Goncalves Filho1,2, John Conklin1,2, Chanon Ngamsombat3, Stephen F. Cauley2, Wei Liu4, Daniel N. Splitthoff5, Wei-Ching Lo6, John E. Kirsch1, Pamela W. Schaefer1, Otto Rapalino1, and Susie Y. Huang1,2
1Department of Radiology, Massachusetts General Hospital, Boston, MA, United States, 2Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA, United States, 3Department of Radiology, Siriraj Hospital, Bangkok, Thailand, 4Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China, 5Siemens Healthcare GmbH, Erlangen, Germany, 6Siemens Medical Solutions Inc., Boston, MA, United States

We compared a highly accelerated post-contrast Wave-CAIPI 3D T1 MPRAGE sequence to the standard 3D T1 MPRAGE in 80 patients undergoing imaging evaluation of intracranial enhancing lesions on 3T MRI. Two neuroradiologists performed a head-to-head analysis to assess the images and found that post-contrast 3D Wave-T1 MPRAGE was up to 2x faster than the standard sequence with no significant difference in the detection of enhancing lesions. The application of highly accelerated Wave-T1 MPRAGE may improve use of MRI resources while reducing patient anxiety and being less prone to motion artifacts.

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