Abstract #3915

Evaluation of Ultrafast Post-Contrast Wave-CAIPI 3D-T1 MPRAGE Compared to Standard 3D-T1 MPRAGE for Evaluating Enhancing Lesions on 3T MRI.

Augusto Lio M. Goncalves Filho^1,2, John Conklin^1,2, Chanon Ngamsombat³, Stephen F. Cauley², Wei Liu⁴, Daniel N. Splitthoff⁵, Wei-Ching Lo⁶, John E. Kirsch¹, Pamela W. Schaefer¹, Otto Rapalino¹, and Susie Y. Huang^1,2

¹Department of Radiology, Massachusetts General Hospital, Boston, MA, United States, ²Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA, United States, ³Department of Radiology, Siriraj Hospital, Bangkok, Thailand, ⁴Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China, ⁵Siemens Healthcare GmbH, Erlangen, Germany, ⁶Siemens Medical Solutions Inc., Boston, MA, United States

We compared a highly accelerated post-contrast Wave-CAIPI 3D T1 MPRAGE sequence to the standard 3D T1 MPRAGE in 80 patients undergoing imaging evaluation of intracranial enhancing lesions on 3T MRI. Two neuroradiologists performed a head-to-head analysis to assess the images and found that post-contrast 3D Wave-T1 MPRAGE was up to 2x faster than the standard sequence with no significant difference in the detection of enhancing lesions. The application of highly accelerated Wave-T1 MPRAGE may improve use of MRI resources while reducing patient anxiety and being less prone to motion artifacts.

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