Abstract #3969

Validating DECOMPOSE QSM with temperature variant ex vivo brainstem imaging experiments

Jingjia Chen¹, Khallil Taverna Chaim², Maria Concepción García Otaduy², and Chunlei Liu^1,3

¹Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, Berkeley, CA, United States, ²LIM44, Instituto e Departamento de Radiologia, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil, ³Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA, United States

A model and corresponding solver for estimating sub-voxel paramagnetic and diamagnetic susceptibility components are validated based on the temperature dependence of magnetic susceptibility. Two pieces of brainstem sample were scanned under various temperature conditions to test the properties of the separated paramagnetic and diamagnetic components.

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