Abstract #3989

Separation of positive and negative susceptibility contrast at 7 Tesla allows for a more detailed characterization of multiple sclerosis lesions

Julian Emmerich^1,2, Frederik L. Sandig³, and Sina Straub¹

¹Division of Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, ²Faculty of Physics and Astronomy, University of Heidelberg, Heidelberg, Germany, ³Division Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany

Quantitative susceptibility mapping (QSM) is known for its usefulness in imaging multiple sclerosis lesions. However, the co-occurrence of demyelination and iron accumulation due to the underlying inflammatory processes limit QSM from truthfully representing histology-like information as phase effects from positive and negative susceptibility sources within the same voxel cancel out in QSM. Here, it is shown that the separation of positive and negative susceptibility sources provides additional information to characterize susceptibility lesions.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.