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Abstract #4015

Clinical evaluation of 4DMRI for lung cancer radiation treatment planning

Jonathan Goodwin1,2, Satomi Higuchi1, Laura O'Connor1,2, Amy Zafara1, Kate Skehan1, Terry Perkins3, Sanjiv Gupta1, Peter Greer1,2, Jane Ludbrook1,2, and John Simpson1,2
1Calvary Mater Hospital, Newcastle, Australia, 2Univeristy of Newcastle, Newcastle, Australia, 3Blacktown Cancer & Haematology Centre, Blacktown, Australia

4D-CT is routinely acquired for lung cancer treatment planning to visualise the extent of tumour motion, to determine the appropriate treatment target volume. However, it can be unreliable in cases of irregular breathing, is susceptible to image artefact in regions close to the diaphragm, and shows generally poor soft tissue contrast. In this study we evaluated an alternative self-navigating 4D-MRI approach in terms of motion detection accuracy, measured tumour volume, and dosimetric differences observed with respect to patients’ existing lung cancer treatment plans.

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