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Abstract #4031

Design of a portable, low-field magnetic resonance sensor for clinical measurement of volemic status

Sydney Sherman1,2 and Michael Cima2,3
1Health Science and Technology, Massachusetts Institute of Technology, Cambridge, MA, United States, 2Koch Institute for Integrative Cancer Research, Cambridge, MA, United States, 3Massachusetts Institute of Technology, Cambridge, MA, United States

A low-field portable MR-based sensor was designed for the acquisition of clinical T2 relaxometry measurements in skeletal muscle. A range of low-field permanent magnet array configurations were modeled with varying sensitive region depths and homogeneous volumes; an optimization score for each design was calculated. The optimal design has a sensitive region 15-20mm from the surface of the magnet, making it capable of acquiring measurements deep into the leg such that the measurement is fully localized to skeletal muscle. The exclusion of subcutaneous fat tissue in the sensitive region will improve sensitivity to fluid shifts within the skeletal muscle.

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