Meeting Banner
Abstract #4072

AcidoCEST MRI pH is strongly correlated with GLUT1 immunohistochemistry in multiple myeloma

Alecio Lombardi1,2, Jonathan Wong1,2, Rachel High1,2, Ya-Jun Ma2, Adam Searleman2, Saeed Jerban2, Qingbo Tang1,2, Jiang Du1,2, Patrick Frost3,4, and Eric Y. Chang1,2
1Radiology Service, Veterans Affairs San Diego Healthcare System, San Diego, CA, United States, 2Radiology, University of California, San Diego, CA, United States, 3Greater Los Angeles Veteran Administration Healthcare System, Los Angeles, CA, United States, 4University of California, Los Angeles, CA, United States

Multiple myeloma (MM) is a malignant plasma cell disease. Adaptive responses to hypoxia may be an essential element in its progression. The purpose of this study was to determine the feasibility of acidoCEST MRI for pHe measurement on a mouse model of MM with comparison with GLUT1 staining.

This abstract and the presentation materials are available to members only; a login is required.

Join Here