Image quality of DWI with single-shot echo-planar imaging (ssEPI) suffers from low SNR in high b-value acquisition. Compressed SENSE (C-SENSE) allow for a reduction of the noise. A total of 26 patients with prostate cancer (PC) underwent mpMRI including DWI with ssEPI and SENSE (EPIS) and DWI with ssEPI and C-SENSE (EPICS). SNR was significantly higher in EPICS than in EPIS. In comparison between ADC of clinically significant PC and ADC of clinically insignificant PC, only EPICS had significant difference. Compared with EPIS, EPICS improves the image quality and may contribute to increased diagnostic performance of tumor aggressiveness in PC.
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