Abstract #4095

Optimal 2D-ROI Method to Measure Apparent Diffusion Coefficient of Lesions in Prostate MRI

Hiroaki Takahashi¹, Kotaro Yoshida², Akira Kawashima³, Num Ju Lee⁴, Adam T Froemming⁴, Daniel A Adamo⁴, Ashish Khandelwal⁴, Candice W Bolan⁵, Matthew T Heller⁶, Robert P Hartman⁴, Bohyun Kim⁴, Kenneth A Philbrick⁴, Rickey E Carter⁵, Lance A Mynderse⁴, Mitchell R Humphreys⁶, and Naoki Takahashi⁴

¹Department of Radiology, Mayo Clinic, Rochester, Rochester, MN, United States, ²Department of Diagnostic Radiology, Kanazawa University School of Medical Science, Kanazawa, Japan, ³Department of Radiology, Mayo Clinic, Arizona, Scottsdale, AZ, United States, ⁴Mayo Clinic, Rochester, Rochester, MN, United States, ⁵Mayo Clinic, Florida, Jacksonville, FL, United States, ⁶Mayo Clinic, Arizona, Scottsdale, AZ, United States

This study evaluated different 2D-ROI methods to measure ADC of prostate lesions on prostate MR. The optimal method for measuring ADC values of suspected lesion for differentiating csPCa and non-csPCa on prostate MRI is 2D-ROI method placed on the lowest ADC area using 6-8 mm2 / 8-9 pixel-size ROI (AUC, peripheral zone lesions: 0.740-0.743 / 0.742-0.743, transition zone lesions: 0.709-0.710 / 0.711-0.713). Use of a standardized ROI size improves interobsever variability.

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