The primary aim of this study was to examine the changes of cortical morphology in patients with unilateral basal ganglia stroke (BS) in subacute phase and evaluate the discrepancies of structural covariance networks (SCNs) between BS and HCs groups by using a seed-based structural covariance approach. The main findings were that BS could cause cortical atrophy of bilateral frontal and temporal lobes and abnormal structural covariance patterns, featured by decreased global efficiency and fragile topological properties in reaction to target attacks. These findings may enable us to better understand the neurobiological mechanisms of behavioral impairment and recovery after BS.
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