Meeting Banner
Abstract #4128

Abnormalities of Cortical Morphology and Structural Covariance Network in Patients With Subacute Basal Ganglia Stroke

Su Yan1, Guiling Zhang1, Weiyin Vivian Liu2, and Wenzhen Zhu1
1Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, 2MR Research, GE Healthcare, Beijing, China

The primary aim of this study was to examine the changes of cortical morphology in patients with unilateral basal ganglia stroke (BS) in subacute phase and evaluate the discrepancies of structural covariance networks (SCNs) between BS and HCs groups by using a seed-based structural covariance approach. The main findings were that BS could cause cortical atrophy of bilateral frontal and temporal lobes and abnormal structural covariance patterns, featured by decreased global efficiency and fragile topological properties in reaction to target attacks. These findings may enable us to better understand the neurobiological mechanisms of behavioral impairment and recovery after BS.

This abstract and the presentation materials are available to members only; a login is required.

Join Here