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Abstract #4173

Neuronal current imaging on clinical whole body scanners: capabilities and limitations

Milena Capiglioni1, Claus Kiefer2, and Roland Wiest1
1Institute for Diagnostic and Interventional Neuroradiology, Support Center for Advanced Neuroimaging (SCAN), University of Bern, Bern, Switzerland, 2Institute for Diagnostic and Interventional Neuroradiology, Support Center for Advanced Neuroimaging (SCAN), Inselspital, Bern, Bern, Switzerland

We evaluated the performance of a new contrast based on the rotary saturation technique to observe oscillating fields induced by neuronal currents. We used Bloch simulations and phantom experiments to study and observe the double resonance effect and the influences of external factors such as field inhomogeneities and relaxation phenomena. We detected oscillating fields in the nT range using the proposed Spin lock on/off contrast. We conclude that this technique can be used to observe oscillating neuronal fields and we propose different methods to reduce the effect of external influences on the signal.

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