Abstract #4178

Simultaneous T1, T2 and T2* Mapping of the Carotid Plaque Using Combined Single- and Multi-echo 3D Golden Angle Radial Acquisition

Yajie Wang¹, Yishi Wang², Haikun Qi³, Rui Guo⁴, Huiyu Qiao¹, Dongyue Si¹, and Huijun Chen¹

¹Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, ²Philips Healthcare, Beijing, China, ³School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, ⁴Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, United States

Previous quantitative techniques for carotid plaque T1 mapping or T1, T2 mapping have been achieved using only one scan. Besides T1 and T2 quantification, T2* mapping of the carotid plaque is also important for the detection of iron deposition, which plays an important role in plaque progression. In this study, a new quantitative technique using combined single- and multi-echo 3D golden angle radial acquisition has been proposed for simultaneous T1, T2 and T2* mapping of the carotid plaque. The quantitative accuracy and the in-vivo feasibility of the proposed sequence have been demonstrated in phantom and volunteer studies.

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