Abstract #4211

Measuring the effect of mechanical loading on deep and superficial cartilage using quantitative UTE MRI

Hanqi Wang¹, Qing Li², Stefan Sommer^3,4, and Yong Lu¹

¹Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China, ²MR Collaboration, Siemens Healthcare Ltd., Shanghai, China, Shanghai, China, ³Siemens Healthcare, Zurich, Switzerland, Zurich, Switzerland, ⁴Swiss Center for Musculoskeletal Imaging (SCMI), Balgrist Campus, Zurich, Switzerland, Zurich, Switzerland

UTE sequences were utilized to quantitatively assess deep and superficial cartilage. Deep cartilage T2* values demonstrated a significant difference in different load-bearing regions while there was no statistical difference for superficial cartilage. No significant change in T2* value of deep cartilage after activity was observed, while T2* values of the superficial layer decreased after activity in both the medial tibial and lateral femoral cartilage, indicating that different bio-mechanical properties exist within the deep and superficial cartilage.

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