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Abstract #4211

Measuring the effect of mechanical loading on deep and superficial cartilage using quantitative UTE MRI

Hanqi Wang1, Qing Li2, Stefan Sommer3,4, and Yong Lu1
1Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China, 2MR Collaboration, Siemens Healthcare Ltd., Shanghai, China, Shanghai, China, 3Siemens Healthcare, Zurich, Switzerland, Zurich, Switzerland, 4Swiss Center for Musculoskeletal Imaging (SCMI), Balgrist Campus, Zurich, Switzerland, Zurich, Switzerland

UTE sequences were utilized to quantitatively assess deep and superficial cartilage. Deep cartilage T2* values demonstrated a significant difference in different load-bearing regions while there was no statistical difference for superficial cartilage. No significant change in T2* value of deep cartilage after activity was observed, while T2* values of the superficial layer decreased after activity in both the medial tibial and lateral femoral cartilage, indicating that different bio-mechanical properties exist within the deep and superficial cartilage.

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