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Abstract #4226

Repeatability and orientation dependence of ultrashort echo time (UTE) T2* mapping at 3T for the whole knee

Zhenzhou Wu1, Stefan Sommer2,3, Xiaodong Zhong4, Kecheng Liu4, Jeehun Kim1, Jillian Beveridge1, Xiaoliang Zhang5, and Xiaojuan Li1
1Program of Advanced Musculoskeletal Imaging (PAMI), Cleveland Clinic, Cleveland, OH, United States, 2Siemens Healthcare, Zurich, Switzerland, 3Swiss Center for Musculoskeletal Imaging (SCMI), Balgrist Campus, Zurich, Switzerland, 4Siemens Medical Solutions USA, Inc., Malvern, PA, United States, 5Department of Biomedical Engineering, University at Buffalo, State University of New York, Buffalo, NY, United States

The connective tissues in the knee joint have ultrashort MR T2* relaxation times. Ultrashort echo time (UTE) sequences can offer a unique tool for measuring the fast-decaying signals in these tissues. However, T2* measures in these collagen-rich tissues are subject to magic angle effect. Previous studies on such orientation dependence and repeatability of UTE T2* in the knee are limited. The objectives of this study were to evaluate the repeatability of UTE T2*, and to investigate and compare the orientation dependence of T2* mapping between UTE and regular gradient echo (GRE) imaging sequences for whole knee imaging.

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