Abstract #4226

Repeatability and orientation dependence of ultrashort echo time (UTE) T2* mapping at 3T for the whole knee

Zhenzhou Wu¹, Stefan Sommer^2,3, Xiaodong Zhong⁴, Kecheng Liu⁴, Jeehun Kim¹, Jillian Beveridge¹, Xiaoliang Zhang⁵, and Xiaojuan Li¹

¹Program of Advanced Musculoskeletal Imaging (PAMI), Cleveland Clinic, Cleveland, OH, United States, ²Siemens Healthcare, Zurich, Switzerland, ³Swiss Center for Musculoskeletal Imaging (SCMI), Balgrist Campus, Zurich, Switzerland, ⁴Siemens Medical Solutions USA, Inc., Malvern, PA, United States, ⁵Department of Biomedical Engineering, University at Buffalo, State University of New York, Buffalo, NY, United States

The connective tissues in the knee joint have ultrashort MR T2* relaxation times. Ultrashort echo time (UTE) sequences can offer a unique tool for measuring the fast-decaying signals in these tissues. However, T2* measures in these collagen-rich tissues are subject to magic angle effect. Previous studies on such orientation dependence and repeatability of UTE T2* in the knee are limited. The objectives of this study were to evaluate the repeatability of UTE T2*, and to investigate and compare the orientation dependence of T2* mapping between UTE and regular gradient echo (GRE) imaging sequences for whole knee imaging.

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