Abstract #4234

B1 Field Inhomogeneity Correction for qDESS T2 Mapping: Application to Rapid Bilateral Knee Imaging

Marco Barbieri¹, Lauren Watkins^1,2, Arjun D. Desai^1,3, Valentina Mazzoli¹, Elka Rubin¹, Andrew Schmidt¹, Garry E. Gold^1,2, Brian A. Hargreaves^1,2,3, Akshay S. Chaudhari^1,4, and Feliks Kogan¹

¹Department of Radiology, Stanford University, Stanford, CA, United States, ²Department of Bioengineering, Stanford University, Stanford, CA, United States, ³Department of Electrical Engineering, Stanford University, Stanford, CA, United States, ⁴Department of Biomedical Data Science, Stanford University, Stanford, CA, United States

Bilateral T₂ mapping is a powerful tool for studying OA changes and investigating the role of between-knee asymmetry. qDESS allows for rapid T₂ mapping but uses a model that requires knowledge of the FA. Hence, B₁ inhomogeneities may affect the accuracy of T₂ measurements. We propose a pixel-wise B₁-correction method for qDESS T₂ mapping exploiting an auxiliary B₁ map to compute the actual FA used in the model. The technique was validated with phantom and with T₂ measurements of femoral cartilage in simultaneous bilateral knee imaging. The results showed that B1-correction can mitigate T₂ variations that were driven by B1-inhomogeneities.

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