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Abstract #4234

B1 Field Inhomogeneity Correction for qDESS T2 Mapping: Application to Rapid Bilateral Knee Imaging

Marco Barbieri1, Lauren Watkins1,2, Arjun D. Desai1,3, Valentina Mazzoli1, Elka Rubin1, Andrew Schmidt1, Garry E. Gold1,2, Brian A. Hargreaves1,2,3, Akshay S. Chaudhari1,4, and Feliks Kogan1
1Department of Radiology, Stanford University, Stanford, CA, United States, 2Department of Bioengineering, Stanford University, Stanford, CA, United States, 3Department of Electrical Engineering, Stanford University, Stanford, CA, United States, 4Department of Biomedical Data Science, Stanford University, Stanford, CA, United States

Bilateral T2 mapping is a powerful tool for studying OA changes and investigating the role of between-knee asymmetry. qDESS allows for rapid T2 mapping but uses a model that requires knowledge of the FA. Hence, B1 inhomogeneities may affect the accuracy of T2 measurements. We propose a pixel-wise B1-correction method for qDESS T2 mapping exploiting an auxiliary B1 map to compute the actual FA used in the model. The technique was validated with phantom and with T2 measurements of femoral cartilage in simultaneous bilateral knee imaging. The results showed that B1-correction can mitigate T2 variations that were driven by B1-inhomogeneities.

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