Synovitis is associated with osteophyte development and osteoarthritis progression. The intensity of synovitis can be quantified by Ktrans, obtained from DCE-MRI using gadolinium-based contrast agent. Diffusion Tensor Imaging (DTI) has shown potential for detecting synovitis without administering contrast agent. This study assessed the potential of DTI to quantify synovitis by comparing DTI parameters (MD, FA) to Ktrans within the whole synovium and adjacent to osteophytes. We found that FA negatively associates with Ktrans in both regions, while MD has a positive correlation only within the whole synovium. DTI is a promising tool for assessing intensity of synovitis in osteoarthritic knees.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords