Abstract #4259

FMRI of Post High-Frequency Focused Ultrasound Ablation of ViM Shows Reduced Ipsilateral Thalamic and Cortical Motor Activation

Anna Crawford¹, Mark Lowe¹, Sean Nagel², Daniel Lockwood¹, Emmanuel Obusez¹, Andre Machado², and Stephen Jones¹

¹Imaging Institute, Cleveland Clinic Foundation, Cleveland, OH, United States, ²Neurological Institute, Cleveland Clinic Foundation, Cleveland, OH, United States

High Intensity Focused Ultrasound (HIFU) in now entering clinical practice, for example to treat essential tremor (ET) by creating small lesions in the thalamus. Due to small size of treatment lesions, treatment success depends critically on targeting, which is classically done using measurements and landmarks. We explore an alternative method using functional imaging to guide targeting and assess efficacy, specifically using 7T task-related fMRI. We present preliminary data of the patterns of BOLD activation in a set of patients before and after HIFU.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.