The fiber orientation distribution function (fODF) can be estimated with diffusion MRI and gives the angular probability density of axon orientations in white matter. Here fODFs, as estimated with constrained spherical deconvolution (CSD) and fiber ball imaging (FBI), are compared quantitatively in order to assess their consistency. An important distinction between these two approaches is that CSD relies on a globally defined, empirical response function while FBI does not. For two measures of anisotropy, similar results are found for the CSD and FBI fODFs. However, a distance metric reveals significant differences in fODF peak directions and fine structure.
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