Abstract #4336

Detecting Magnetic Resonance Changes in Brain Structure and Function During Stroke Rehabilitation

Jonathan Taylor¹, Oun Al-iedani^2,3, Saadallah Ramadan^3,4, Neil Spratt¹, and Sarah Valkenborghs⁵

¹School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia, ²School of Health Sciences, University of Newcastle, Newcastle, Australia, ³Hunter Medical Research Institute, Newcastle, Australia, ⁴Faculty of Health and Medicine, University of Newcastle, Newcastle, Australia, ⁵University of Newcastle, Newcastle, Australia

Using Magnetic Resonance (MR) data acquired as part of a feasibility study in stroke rehabilitation, a novel post-processing pipeline was designed and implemented to explore metabolic factors with MR Spectroscopy (MRS). The stroke study looked at the effect of aerobic exercise performed immediately prior to the usual task-specific rehabilitation training. Examining the clinical motor function results in relation to the metabolic data revealed by the MRS pipeline showed some interesting correlations among metabolites and rehabilitation outcomes.

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