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Abstract #4341

Monte Carlo Simulation Study of Asymmetric Spin Echo and Preliminary Estimation of Vessel Size Index

Jian Shen1 and John Wood1,2
1University of Southern California, Los Angeles, CA, United States, 2Children's Hospital Los Angeles, Los Angeles, CA, United States

Asymmetric spin echo (ASE) sequence is a technique for mapping oxygen extraction fraction (OEF) and venous cerebral blood volume (vCBV). However, there might be an overestimation of vCBV due to the diffusion effect related to vessel size. In this study, we use Monte Carlo simulation to study this effect and investigate the feasibility of estimating vessel size index from ASE data.

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