Abstract #4354

DTI-based Longitudinal Assessment of Stroke Recovery at 21.1 T

David C. Hike^1,2, Taylor A. Ariko^1,2, Frederick A. Bagdasarian^1,2, Shannon Helsper^1,2, and Samuel Colles Grant^1,2

¹National High Magnetic Field Laboratory, Florida State University, Tallahassee, FL, United States, ²Chemical & Biomedical Engineering, FAMU-FSU College of Engineering, Tallahassee, FL, United States

This research utilizes DTI and graph theory to provide a method for monitoring the progression of structural stroke recovery at 21.1 T. Edema that occurs for multiple days post the initial ischemic limits the ability for tractography to be used for any meaningful connectivity analysis before day 5. After this initial phase, graph theory provides metrics for determining the progression of recovery in major white matter regions of the ischemic brain. This method could be utilized as a means for determining the efficacies of different treatments compare with standard stroke recovery.

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