Abstract #0001

Self-gated 3D Stack-of-Spirals Ultra-Short Echo-Time Pulmonary imaging at 0.55T

Ahsan Javed¹, Rajiv Ramasawmy¹, Kendall O’Brien¹, Christine Mancini¹, Pan Su², Waqas Majeed², Thomas Benkert³, Himanshu Bhat², Anthony F. Suffredini⁴, Ashkan Malayeri⁵, and Adrienne E Campbell-Washburn¹

¹Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, United States, ²Siemens Medical Solutions USA Inc., Malvern, PA, United States, ³Siemens Healthcare GmbH, Erlangen, Germany, ⁴Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD, United States, ⁵Department of Radiology and Imaging Sciences, Clinical Center, Department of Health and Human Services, National Institutes of Health, Bethesda, MD, United States

Synopsis

High-performance 0.55T MRI is promising for lung imaging due to the reduced susceptibility artifacts. However, high-resolution lung imaging is still challenged by low proton density and SNR. 3D spiral acquisitions can be used to improve SNR-efficiency, but these readouts are susceptible to trajectory errors and blurring from concomitant-fields, which are amplified at lower field strengths. Here we present a self-gated, ultra-short echo-time, stack-of-spirals acquisition which leverages rapid inline corrections for trajectory imperfections, trajectory dependent navigator signal fluctuations, and concomitant-fields to enable robust 1.75mm isotropic lung imaging at 0.55T. We also demonstrate our technique in healthy-volunteers, patients with lung-nodules and COVID-19.

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