Diagnostic Accuracy of Spiral Whole-Heart Quantitative Adenosine Stress Cardiovascular Magnetic Resonance with Motion Compensated L1-SPIRIT
Jonathan A. Pan1, Austin A. Robinson2, Patricia Rodriguez Lozano1, Yang Yang3, Stephen McHugh4, Eric M. Holland5, Craig H. Meyer6,7, Angela M. Taylor1, Christopher M. Kramer1,7, and Michael Salerno8
1Cardiovascular Division, Department of Medicine, University of Virginia Health System, Charlottesville, VA, United States, 2Division of Cardiovascular Diseases, Division of Radiology, Scripps Clinic, La Jolla, CA, United States, 3Biomedical Engineering and Imaging Institute and Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States, 4Department of Internal Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States, 5Division of Cardiology, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States, 6Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, United States, 7Department of Radiology and Medical Imaging, University of Virginia Health System, Charlottesville, VA, United States, 8Division of Cardiovascular Medicine, Stanford University, Palo Alto, CA, United States
Variable density spiral (VDS) pulse sequences with motion compensated compressed sensing reconstruction allow for whole-heart quantitative assessment of myocardial perfusion but have not yet been clinically validated. In this study, we showed that whole-heart VDS stress perfusion has good diagnostic accuracy and ischemic burden evaluation. No significant difference was seen between visual and quantitative diagnostic performance and ischemic burden measurements.
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